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A Lecture on Psychedelics & Monoamine Oxidase Inhibitors: DMT & 5-MeO-DMT

  • Thymele Arts 5481 Santa Monica Boulevard Los Angeles, CA, 90029 United States (map)


This is the third part of a 5-part workshop series geared toward providing a foundation for understanding the psychopharmacology and clinical research of the most commonly encountered psychedelic compounds as well as practical information for safe psychedelic use. Seating is limited so sign up today!


  • August 29, 2019

  • September 26, 2019

  • October 24, 2019


Doors Open: 6:30pm

Event Begins: 7:00pm - 9:00pm


Thymele Arts - 5481 Santa Monica Blvd, Second Floor, Los Angeles, CA 90029.

The parking structure entrance is around the corner on Western.


Series Description:

III. August 29: Psychedelics & Monoamine Oxidase Inhibitors: DMT & 5-MeO-DMT

Monoamine Oxidase (MAO) is an important metabolic enzyme involved in the metabolism of several neurotransmitters and tryptamine psychedelics such as DMT and 5-MeO-DMT. While inhibition of this enzyme is critical to making DMT orally active as part of the mechanism of ayahuasca, it can be unsafe and even lethal to combine other drugs or psychedelics with MAO inhibitors (MAOIs). The third installment of the series will focus on the combination of monoamine oxidase inhibitors (MAOIs) with psychedelics as well as other drugs.

IV. September 26: Psychedelics Beyond Serotonin: Ibogaine & Ketamine

While most psychedelics produce their effects by modulating serotonin, there are exceptions of worthy mention including ibogaine and ketamine. While vastly different in their effects, both ibogaine and ketamine appear to modulate either glutamate or opioid systems. Ibogaine is often touted for its powerful anti-addictive properties, although it carries risks of cardiotoxicity. Ketamine has built a strong evidence base in the treatment of depression, amongst other refractory conditions. The fourth installment will take a closer look at each of these ‘novel’ psychedelics.

V. October 24: Psychedelics & Psychotropics: Mechanisms of Drug Interaction

The fifth and last installment in this series will focus exclusively on the potential for drug interactions between psychedelics discussed in installments I–IV and other medications or supplements people may be using. While the aim is to cover a broad range of possible interactions, a focus will be placed on interactions with traditional psychotropics including antidepressants, benzodiazepines, stimulants, and antipsychotics. It is recommended to attend installments I–IV to allow for optimal understanding of materials covered in this installment.

Speaker Bio:

Benjamin Malcolm teaches psychopharmacology, practices as a clinical psychiatric specialist, and performs research on psychoactive drugs including psychedelics. His educational background consists of a bachelor’s degree in pharmacology, a doctorate of pharmacy, a master’s degree in public health and specialized post-doctoral training in psychiatry. He’s a lover of nature, exercise, music and consciousness as well as being a husband and father. He’s passionate about psychedelic drugs and envisions a society in which they are available in safe and supported settings for psychospiritual well-being, personal growth, ceremonial sacrament, and treatment of mental illness. Additionally, he runs a psychopharmacology consulting service on his website,, to help those in need for an informational risk evaluation of psychedelic use.


PsychedeLiA: Psychedelic Integration, Los Angeles is a collective of professionals and peers interested in the potential psychological and spiritual healing properties of psychedelics. PsychedeLiA events are intended for the purpose of educating about mindful & safe integration of entheogenic experiences, offering emotional support, and creating meaningful connections between community members.

PsychedeLiA's Mission Purpose:

We are a collective of professionals and peers interested in the potential psychological and spiritual healing properties of psychedelics.

PsychedeLiA’s program takes a harm reduction approach with these objectives:

  1. We aim to provide accurate information about mindful and safe preparation, engagement and integration of entheogenic experiences.

  2. We aim to offer educational tools to users of psychedelics and to their support systems.

  3. We aim to offer emotional support to individuals and groups who are curious about, are planning on exploring or have explored psychedelic states.

  4. We aim to create meaningful connections between community members.

Very Important Disclaimer: We do not encourage or condone any illegal activities, the purchase, sale, transfer, or use of any illegal substances, or partaking in any unlawful activities related to illegal substances. Please do not bring, buy, sell, transfer, or arrive on any illegal substances, or swap information on how to acquire them. Thank you for respecting our safe community space.



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#Psychedelic #Integration #Ayahuasca #Shamanism #MDMA #LSD#Psilocybin #SanPedro #Cannabis #SpiritualEmergence #Entheogen#PTSD #posttraumaticstressdisorder #CPTSD #anxiety #mentalhealth